CC268, my background is quite similar to yours. Life-long car junkie, have changed out the suspension of just about every car I've owned, built a Porsche 914 with a Chevy LS1 V-8 conversion, model planes for 30 years etc. It sounds like you could handle the build, no problem. The dream of building you own aircraft just has to burn brightly enough inside to endure those long hours of construction. There are some very thankless tasks...it seems like about 1/3 of the time is devoted to deburring...every...single...piece of aluminum that makes up the airframe. Even so, I couldn't wait every day to get out in the garage and build the next control surface or subassembly. Finish the rudder? Hoist it high above your head and have someone take your picture with it. I did; it helps with motivation.
They say this a lot on VAF...one bite of the elephant at a time. Don't get overwhelmed with the enormity of the project; just laser-focus on the task at hand. Hit a bit of a wall? Research some more through the VAF archives or look at other people's build logs and ruminate on a solution. In the meantime, go build another piece. Hey, it'd be fun to make the elevator bellcrank right now, or whatever.
Fiberglassing is messy and one of my least favorite things, but I became pretty good at it. I highly recommend spending a little more money here and getting intersection fairings for the landing gear from Fairings Etc. The Van's stuff is far cheaper, but requires a ton of additional 'glassing and filling, where the other bits are pretty much ready for paint out of the box.
If you've wired simple circuits, you can handle a plane. My RV is bar far the most complicated wiring project I've undertaken...before that it was rc planes and cars, and the 914 required some additional wiring/relays. For me, the Vans wiring kit was a great starting point, as it includes a pretty basic schematic for the whole plane that I followed religiously. You just run one wire at a time, one circuit at a time, one switch at a time and pretty soon you're ready to tie-wrap the whole bundle together. Great video tutorials out there on wiring on EAA and SteinAir websites.
The panel is the piece de resistance, by far the most rewarding thing I did. Pretty easy to wire up the EFIS, transponder, etc. with serial ports minimizing the number of wires. So fun to sit in the "canoe" and mock up the panel, figuring out the perfect location for each switch, lamp and display. RV panels are like snowflakes...no two alike.
Motivational before/after pics--In the garage, circa 2015, and Oshkosh this year: