Yep, we all "know a guy without a degree" that is doing well. But, I would guess we know even more who don't have a degree that ain't doing well, or like the poster a few up, live with just a bit more uncertainty about job prospects because of the lack of a degree in a potential reorganization and going out on the open market.
I have an uncle that is in that boat, got laid off from a major bank during a reorganization and has had to spend the last 8-10 years "consulting" on IT projects. He bills a high rate, but you can tell there is stress from the "temporary" nature of being a forced consultant in IT.
It can certainly be done, but it is a harder path, and, I would never advise someone to take a harder path just to avoid World Geography class. I never took a Geography class, but I would likely enjoy it. Always been a collector of maps.