It really depends on weather and winds aloft the day I'm going. There's no big deal to flying at altitude in a turbo equipped plane, UNLESS the turbo craps out on you lol, but you typically have plenty of time to slowly drift down. Most planes that would be equipped with a turbo won't have a problem maintaining 12,000-14,000 without it as long as you have a waste gate you can open. Turbos are pretty simple and reliable so I wouldn't particularly worry about that. West bound over the mountains is typically down wind, so you're unlikely to get in trouble there, just remember, if the plane climbs on it's own, pull back and climb with it, if the plane is dropping out of the sky, put the nose down and go for airspeed and get out of the down draft. If there is a crosswind component, stay on the windward side of the mountains, in their lee is where you find the ugly air. If the weather isn't good, I'd head south down the valley and turn left around Vegas and point it towards Alamosa CO. From there routing is just steering around the weather cells. If it's one of those days when the storms make it from Canada to Mexico, the further south you are when you hit a line of T-Storms the higher the bases will be, I never penetrate the clouds through there by my choice, too much not fun stuff in there. I stay underneath and drive around the cells that are actively dumping, I also keep up on the winds aloft so I can stay upwind of the the anvil side of the big cells, remember, the winds at 30-50k where some of these anvils are can be opposite to the winds you are in, so when I come up on a line I call in and get a winds aloft update in real time if I can't see the tops. Green skies are the enemy, never drive into green, it's worse than black, green is hail.