I think a lot of high-wings are optimised for applications where ground clearance, visibility, and access are more important than speed, e.g. off-airport landings, float and ski ops, skydiving, SAR, pipeline inspection, etc. etc. There are some speedy high-wings, like the Cessna 210, but they usually don't have wing struts (except for the earliest 210s). I think if you see a high wing with wing struts, speed probably wasn't the top design goal — but then again, when's the last time you saw a Mooney on floats?