OP,
do a little math. From school, 20 minutes to airport (guessing). 30 minute fuel and preflight. Now find out the speed for a C172 and multiply by 500 miles. Add 30 minutes at destination for tie down, and other post flight items. Now you need a ride to home, etc.
Since you are still in high school you don't know your schedule yet, but I doubt you will be able to fly Friday after class home before dark. No problem after dark for some people.
You didn't say where you are located. Texas is very different for 500 nm than the northern states, over mountains etc. Right now, there are plenty of areas that are dark by 5pm. Getting back to campus on Sunday is the same equation in reverse. In short, it's a handful for a weekend. It would be a great experience, but it will be time consuming. I haven't even mentioned weather challenges.
If this is for trips home over long breaks such as thanksgiving, Xmas, spring break etc., I'd suggest renting or airlines, then rent/fly while home. You can learn different planes and see which you like best, among other advantages.
FYI: I have 2 kids in college, one with her pilot license. I am familiar with the demands of flying and college life. As others have stated, start on your PP now, get it done before college. Spend available college hours learning to extend your comfort zone a little, work on instrument, occasionally fly home. Buy a plane down the road. When you chose a college, see if they have a flying club or team.