The Turbo-Normalized option for Bonanzas provides a lot of utility. There are some variations that you want to keep in mind...
I'd say most, but not all, TNed birds come with an IO-550 mod for those that didn't originally have it. That's an extra 15 ponies.
To really get the most out of a TNed bird, you really need tip tanks. These come in various flavors, but most are either the 15 gallon or 20 gallon variety, so you wind up between 104 and 114 gallons of fuel.
The combination of TN mods and tip tanks provides a variety of gross weight increases. There are two TN mods (Tornado Alley & Western Skyways). I am most familiar with the TAT setup. It doesn't provide any gross weight increase (GWI) for V35s, but provides a good bump for both the A36 and F33A. The GWI is actually quite significant for the F33A (on the order of 350 lbs), and turns it into quite a hauler.
Tip tanks also provide a GWI for most Bonanzas (both DeShannon and Osborne). V-tails & Debbies (33s) (depending on year) get up to 200lbs, and the A36s can get more.
The mods don't "stack", meaning that you cant add the GWIs together, but you do wind up with MTOWs with tips/TN of 3600 lbs for V35s, 3750ish for F33s and 4000 for the A36s. That leads to average useful loads of 1100-1400ish lbs unless you've got a lot of equipment or factory air conditioning (the aftermarket AC weighs less).
Real world performance depends on the generation of the system you have (latest TAT TN setups have a ram induction intercooler), but speeds are about the 180 range above 8000, 185 in the low teens. 190 in the mid teens, and touching 200 above 16k. Practically any ordinary certified piston is going to require flight above 10k (and probably above 15k) to get to 200 knots, unless it has some kind of exotic mod (turbine). Fuel flow is around 16.5 to 17.5 GPH depending on your setup. There seems to be enough variation in the TN setups and tip tanks that you really want to work the numbers for the particular bird you are looking at. Vs seem to be the fastest (light weight S35s are the speed masters), with F33s close behind, a A36s a tad slower. The TAT system is fully automatic. Wide open throttle for climb and cruise. 2500 RPM and lean to your desired fuel flow for cruise. The only time you pull the throttle back is for descent.
Bonanzas have all kinds of setups, so you need look at the weight and balance for the individual airplane you are looking at and your specific mission. The CG envelope narrows as the weight increase, and some airplanes it is possible to be in CG for takeoff, but move out of CG as fuel burns off. The empty CG can be tweaked with ballast, and the TN mod adds a good amount of weight to the nose. Aftermarket O2 can also add some weight.
V35TCs/A36TCs are a different animal, and B36TCs a different animal yet. Some report getting very good results with the factory turbo birds, but good engine baffling is the key. Some also report that getting them to efficiently run lean of peak is very difficult. All can be retrofitted with a TN mod. Many consider the B36TC with the TN mod to be the ultimate piston cruiser in that category. It has a longer wing, similar to the Baron, and doesn't require tips to carry a lot of fuel.
The key here is to realize that there is a LOT of variation in setups. Certainly you can group Bos into certain categories, but you really need to examine the setup and CG of the aircraft individually to make sure it fits your mission.
There's probably more than you could ever read on Bonanzas (and Barons) over at Beechtalk.com. It's free.
If your folks aren't keen to wearing O2, then you need a different solution. You can do a Malibu/Mirage, a P210 or similar, or you can consider a twin like a 58P Baron or Cessna 340. Pressurization in and of itself is not a huge MX hassle (assuming the system is setup correctly & no leaks), but it often comes on aircraft that have other components that required increased attention...turbos, electrical, environmental...etc.
My $0.02...
Richman