Just, Wondering how safe aircraft of this type really are, to fly single pilot? Anyone remember Thurman Munson?
Not at all, in fact, the biggest single difference in the safety record of 121 vs 91 is that 121 runs a crew cockpit. When things start going wrong they go wrong fast and the ability to delegate control duties and and diagnostic duties to two different people is a huge advantage.
IMO the safety of an autopilot is vastly over rated as it is one of the most fallible systems in the plane, in fact an autopilot failure is what precipitated AF-447. Autopilots are highly complex electronic-electromechanical devices and do a lot of work with little maintenance, that in itself does not bode well. I have very few hours under autopilot because most of the planes I've flown with autopilots, the AP was either unreliable or broken. In over 2500 hours of flying a whole bunch of different plane, there are only two where the autopilot has not failed me, Av Shilo's Comanche and Bob Gerace's T310R; and these guys spend big budget constantly maintains their equipment, yet still don't operate failure free, they just have them every couple of years rather than every couple, or even every, flight. They also train a lot.
The funny thing is I am completely relaxed hand flying, Bob put a Pulse Oximiter on me as I was doing a black hole departure out of Alamosa and says, "58, how the hell do you have a pulse of 58 when hand flying a black hole departure with mountains all around you?"
On autopilot I feel like a CFI with a schizophrenic student, watching for the first sign of them flipping out and going suicidal.
Once you learn that trim is a continuous process from take off to landing. During cruise you are constantly giving it a nudge to compensate for the fuel burn off reduction in drag. Unless it is really turbulent, I barely work flying.
Personally I think considering an autopilot as your safety back up for control while you diagnose is not that solid of thinking when there is a very good chance what you are diagnosing is going to be autopilot related.