misteryan
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misteryan
The FDA told us things that were not true. Trying to avoid politics.What happened Monday?
The FDA told us things that were not true. Trying to avoid politics.What happened Monday?
And Monday was not a good day for the FDA's trustworthiness.
The FDA told us things that were not true.
No argument from me on anything you say here. I won't be waiting until phase 3 results are available. I will be waiting until it's reasonably clear that the vaccine isn't going to kill or maim half the people that take it. In other words, I'll wait a bit to make sure it's a disaster.There is more than one pharmaceutical-regulating government agency in the world that will be looking at the vaccine trial data. The FDA isn't high on my list of the one's I'll be trusting either.
I'll take my chances with a reasonably-well test vaccine vs. the known destruction of bodily functions COVID can cause in many cases where it doesn't kill you. I'm not that worried about getting killed by COVID, I am concerned about getting a permanently-debilitating illness from it.
For those of you in the "I'm young and healthy and so is my family" camp, I urge you to better understand how herd immunity works with vaccines. I have people close to me who are immunocompromised and can't be vacinated. That is a legitimate reason to not get vaccinated. But those people rely on everyone around them, and every one around those people, etc., to get vaccinated. No vaccine is 100% effective either, so some who get vaccinated still won't be protected, or may be protected from getting very sick but can still pass the virus others. The vaccine (or, more than likely there will be more than one available) don't need to be 100% effective if enough people get vaccinated. If only half the population get's vaccinated, that may not be enough to protect the immunocompromised.
Is there a chance that you might have a sore arm or a mild fever for a few days after vaccination? Yes. But by the time a properly vetted vaccine is released from Phase III trials, any reaction more severe than that will be a "lottery win" 1:100,000 chance.
Google “proven to reduce mortality by 35 percent.” The news stories will come up. Not even remotely true, and the FDA admitted so afterwards.ok, I understand avoiding politics... but how about a hint. I'm pretty sure that the FDA announces all sorts of things every single day
Google “proven to reduce mortality by 35 percent.” The news stories will come up. Not even remotely true, and the FDA admitted so afterwards.
Not necessarily true, though I get your point. I just refuse to join the post-truth world. I got admonished by a friend yesterday for wanting context before being outraged about something. Who needs context?I’m pretty sure nobody wants to believe any good news anymore. If it’s good, it must not be factual. Only bad news is true nowadays.
That is a valid point. But the risk is not zero, and when there is a non-zero risk, individuals should evaluate their own tolerances to that risk and make a responsible decision.
Ugh, this is really frustrating to hear. People believe whatever they want to believe, and love a good conspiracy theory. Who here knows someone that has been directly harmed by a vaccine?
Or, a system where people can inform themselves and evaluate the potential motivations of those whose decision making affects the population.The problem is we have allowed a system to develop where any random person's google search has equal weight in public health decision making as a team of scientists with hundreds of years of combined experience among them.
No argument from me on anything you say here. I won't be waiting until phase 3 results are available. I will be waiting until it's reasonably clear that the vaccine isn't going to kill or maim half the people that take it. In other words, I'll wait a bit to make sure it's a disaster.
And I will not under any circumstances take anything that's approved before November. Ever.
For those of you in the "I'm young and healthy and so is my family" camp, I urge you to better understand how herd immunity works with vaccines. I have people close to me who are immunocompromised and can't be vacinated. That is a legitimate reason to not get vaccinated. But those people rely on everyone around them, and every one around those people, etc., to get vaccinated. No vaccine is 100% effective either, so some who get vaccinated still won't be protected, or may be protected from getting very sick but can still pass the virus others. The vaccine (or, more than likely there will be more than one available) don't need to be 100% effective if enough people get vaccinated. If only half the population get's vaccinated, that may not be enough to protect the immunocompromised.
Is there a chance that you might have a sore arm or a mild fever for a few days after vaccination? Yes. But by the time a properly vetted vaccine is released from Phase III trials, any reaction more severe than that will be a "lottery win" 1:100,000 chance.
That's not the case. Phase III trials provide most of the safety data. Phase II trials asses short-term side-effects; phase III trials asses long-term side effects. You might wind up not getting a sore arm, but getting cancer, heart problems, liver or kidney problems, etc., instead.
And Monday was not a good day for the FDA's trustworthiness.
Funny you mention this...I got West Nile about 8yrs ago...friggin' brutal for about 4 days. Started with almost instant crazy pain in upper back / neck. I thought it was because I was sitting funny and crinked my neck or something. Then the fever rolled in about 3hrs later and I just remember sweating and massive headache for 3 days until it broke on the 4th day. If Covid is worse I'll risk the vaccine but prefer to wait at least 6 months.I'm still waiting for a West Nile vaccine, I know some people who got really messed up from that who are probably better off dead. One of them was a 24 year old woman with no significant previous medical history.
Unsure.
I didn't even receive the immunizations that were required in the mid '60s for children to be allowed in public school.
Remember Vioxx? Thalidomide? Fen-phen? And a whole host of others. https://en.m.wikipedia.org/wiki/List_of_withdrawn_drugs
This vaccine or any new drug cannot be proven safe for at least 72 years.
Huh?
I saw Dr. Bruce respond in either this thread or a similar one that the FAA doesn't care about vaccines, although they would care about someone participating in a trial because the drug isn't approved yet. I don't recall ever putting vaccines on my medical application.The FAA medical stuff w/r to the vaccine was not something I expected when thinking up the poll.
Recently a 71 year old drug was declared too dangerous to let a doctor prescribe it.
You're absolutely correct that evaluation continues after approval, but not every serious adverse event relates to toxicity. Phase 3 trials are (mostly) to assess long-term safety.Phase III are mid-term toxicity. Long term assessment comes in the marketplace after the drugs are approved. Remember Vioxx? Thalidomide? Fen-phen? And a whole host of others. https://en.m.wikipedia.org/wiki/List_of_withdrawn_drugs
Long-term toxicity (aka side effects) cannot be fully evaluated in a Phase III, especially one on a compressed timeline like the Covid vaccine.
It depends what you mean by 'long term'. If we're talking years, I don't think you are correct. The perfect is the enemy of the good. That applies to the way many people think, not just about various aspects of the virus, but life in general.Phase 3 trials are (mostly) to assess long-term safety.
The perfect is the enemy of the good. That applies to the way many people think, not just about various aspects of the virus, but life in general.
Phase 3 trials generally last several years.It depends what you mean by 'long term'. If we're talking years, I don't think you are correct. The perfect is the enemy of the good. That applies to the way many people think, not just about various aspects of the virus, but life in general.
Then they're useless in this context.Phase 3 trials generally last several years.
Essentially, yes. Absolutely correct. There are some drugs that are being tested for use against covid that have been thoroughly tested and approved for other uses, like HIV meds. They're anti-virals. So some have a track record. But any of the Operation Warp Speed drugs are "fingers crossed".Then they're useless in this context.
Right, so some people are making a different risk/reward calculation than others. Is that so surprising?Essentially, yes. Absolutely correct. There are some drugs that are being tested for use against covid that have been thoroughly tested and approved for other uses, like HIV meds. They're anti-virals. So some have a track record. But any of the Operation Warp Speed drugs are "fingers crossed".
[QUOTE="misteryan, post: 2969067, member: 43491"I'll wait a bit to make sure it's a disaster.
Sure, so long as they understand what the risks and rewards are. I have strong doubts that many people will. Then again, it could certainly be argued that we essentially have no choice as a society.Right, so some people are making a different risk/reward calculation than others. Is that so surprising?
You think your own judgement is superior to those who may disagree, so you want the government to enforce your view. So much for live and let live.Sure, so long as they understand what the risks and rewards are. I have strong doubts that many people will. Then again, it could certainly be argued that we essentially have no choice as a society.
I don't know what leads you to that conclusion. When a national leader and the head of the FDA stand in front of a bank of TV cameras and tell the world something that is patently untrue, it is not only misinforming people, but it also undermines peoples' confidence in anything else they have to say in the future. In other words, it's hard for people to make informed decisions when they're being (deliberately) misinformed. Contrary to what you say here, I want people to get correct information so that they can make the best decisions for themselves.You think your own judgement is superior to those who may disagree, so you want the government to enforce your view. So much for live and let live.