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Guess what they take for lupus. Hydroxyclorioquine. So they already have it in their system.
Same being reported for sarcoidosis patients both on hc and steroids. (Rarely at the same time.) Also holding for a number of other immune modifiers.
Surprising considering most are well into “big time co-morbidity” territory.
Seems like anything that mellows the immune over-reaction is generally better than nothing.
On the flip side the medical folks are suggesting caution on the vaccines due to possible autoimmune reactions for most autoimmune disorder patients. However one sarc person out of a group of five digits has done it without autoimmune reaction, but with a definite “didn’t feel good for a while” reaction in a Phase 3 trial.
Not exactly statistically significant but we all said congrats. She had some incredibly high risks so... good for her.
As far as why I brought it up, vaccines are lovely — but you still have an enormous logistical problem of distribution to solve. Tons of people are going to still catch this thing long before an approved vaccine can be distributed widely.
Might as well pay attention to the outpatient options and numbers as closely as the vaccines.
They won’t be fast. Months minimum. A few “essentials” will be offered it first. Take a while.
Thanks for the background on the “study”.
It does still anecdotally match what we’re seeing in the autoimmune groups. Most on these drugs and immune modifiers aren’t having the fatal over-reaction.
The other interesting reaction is a “not only no but hell no” reaction from the majority of the TM group after the UK trial may have triggered TM in a coupe of recipients.
Most TM patients would take death or other long term ***treatable*** issues over any chance of additional neuro damage and resulting permanent pain or paralysis. TM has no treatment. A very large percentage try would rather die than risk a worse case of TM.
(Just passing on the general feel of that group. Not trying to be a downer. TM really is that bad.)
There will also be a lot of fascinating things learned in five or so years I bet, from how autoimmune patients’ bodies reacted to it.
Sarc group is all over the map, generally happy about the continued news of lower reactions on virtually every drug normally prescribed, but usually depending on amount of existing lung damage, that changes how wary the person is of all of it.
In other words a subset that knows they already don’t have any real lung capacity to catch a cold, much less Covid, the flu, anything.
The fascinating one has been the TM crowd though. Nearly violent reaction. They want that side effect fully investigated and that whole one shut down hard if TM is a true unexplained risk factor.
That’s how much none of them want to see any of you have that as a side effect. They’re truly angry at that possible side effect.
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