I owned a Saratoga II TC for a few years and transitioned to a Meridian in 2007 or so. At the time I purchased the Meridian, my mission was primarily flights between 150 and 300 miles, although I did longer flights occasionally.
What I discovered is that with the increased capability in my equipment, pressurization, FIKI and the ability to get over most weather, my mission dramatically changed. I started using the airplane for more of my travel, including missions over 1,000 miles.
The Meridian is a great airplane for the owner that is looking for flexibility in missions. It can handle longer flights but you won't get crushed on short flights. The Meridian really wants to fly in the mid to high 20s, but for short flights, I would usually fly in the high teens. There is a fuel penalty for being that low, but it is not that bad, especially as compared to the TBM.
Several people have mentioned the TBM as an alternative to the Meridian and JetProp, but there is a quantum leap in acquisition and operating costs and the airplane, which is outstanding, is not nearly as efficient as the PA46 turbines.
If you have the ability and the desire, you will really enjoy transitioning to a turbine. The pressurization is a game-changer and you will find that the performance will allow you to use your airplane for much more than you previously did.
Good luck with the research. Let me know if I can answer any questions for you.
Abram Finkelstein
EA50
N48KY