You can lose all GPS, one or more ADHRS, one or more ADC's, magnetometers, and have power failures. So mimicking those modes by covering up relevant parts of the panel, or pulling CB's to those devices can mimic real life failures.
Real international flight. Military GPS jamming took out both aircraft GPS's as well as cell phone and iPad GPS's. lasted about an hour iirc.
You lose all ADS-B info including traffic, real TCAS still works if you have it.
You lose the moving map although it will go into dead reckoning mode
Lose all GPS approaches and GPS as DME
You lose GPS track outside of limited DR dead reckoning mode
Lose fuel over destination
You lose winds at altitude
You lose terrain and TAWs
You lose synthetic vision
You lose ground speed
You still have VOR's but without DME, you have to use crossing VOR radials to determine position.
Bad magnetometers take out the compass
ADC's lose speed, altitude, and in some less robust PFD's even attitude and roll
ADHRS lose attitude info
Still worth practicing flying with limited info, and if possible have redundant ADC's,. ADHR's, power sources on separate busses, Magnetometers, etc.