The biggest of which to me are the rollers to keep the fan assembly tracking. Each will require maintenance, lube, and introduce points of failure.. I count 22(?) of them
At 1500 lb thrust, each of those rollers/bearings will only see 70 lb of force. It looks like they're about 1/16 of the radius of the spool, so at 5000 rpm (did he give that figure somewhere? I can't recall) they'll be turning 80,000 rpm. I'm not double-checking my math for obvious reasons. But what could possibly go wrong with those numbers?
If memory serves, Mr. Muller comes to the world from a software background. People who write code often fall into the trap of finding some small thing they dislike about existing software, arrogantly thinking that they can make a better piece of software from scratch,* and being right often enough at a small scale that the positive feedback loop puts them high on the Dunning-Kruger peak for all other pursuits. Compared with programming, aerospace provides a more complicated, less predictable,** and less forgiving*** environment to navigate down from the peak to the trough.
* Thus the proliferation of "exciting" and "unique" programming languages and software libraries that scratch one person's itch but crash as soon as they see inputs that their author was too narrowly focused to consider.
** If you write a 5-line function and test it against a range of inputs, you can generally trust that it will work the same when you put it into a 25-million-line project. If you design a 5-inch rudder and test it anywhere, you cannot trust that it will work the same when you put it on even a 250-inch airframe.
*** For all but the lowest-level programmers these days, the worst-case scenario in unit testing is that you instantaneously get a core dump that shows you where and generally why your program crashed. Two minutes later, you're unit testing a fix. For airframe testing, even the best-case failures take a long time to adjust and re-test, with a worst case time measured in lifetimes, namely that of the departed test pilot.