I’m not saying no, just would want to run the takeoff performance numbers and climb numbers for the area the strip is in first. A 100’ estimated change in strip elevation is about a 4% grade. Depending on conditions, you could get yourself into a situation where you can’t get off the ground safely, even going down hill. Lost a good friend, his wife and son to an accident like that. The difference in their situation was much smaller grade. Stall/spin on takeoff, where climb performance was under 200 fpm.