Easy answer: No. You could take out the O2 sensors and remove the cats and run it. But you will have problems later on. Av gas is not friendly to electronic fuel injection as well.
Just one question, what RPM do you see in your engine? Av-gas is leaded, yes, but also designed to run in a low compression engine aircraft engine, at 3000 rpm, or less, at a steady RPM. Like an airplane engine does. My race engines never ran as low as 3000 RPM except at the start of the race. My race engines were designed for wide open throttle to closed throttle, repeat up to 1000 times per race. (2 straight aways) Something airplane engines don't do.
I raced cars for years, had a race fuel business and was a gas specialist on a team that ran a car in the Winston Cup Series. So I am sure that with my experience there will be someone here to tell me I don't know squat. Listen to that person, ruin your engine, then bring it to me and I will tell you what went wrong. The only race people that ran av gas at the race tracks were also airplane people and it was in their planes. With that said, a decent engine builder can build an engine to run on avgas, but a good engine builder won't do it. He values his reputation too much.
After asking around, I guess you could run a little av gas in the super unleaded to get a little lead in it. Say around 1 gallon avgas to 9 gallon super. It won't raise the octane number. Just make sure the super unleaded wasn't made with methanol in it because lead and methanol won't mix together. The ethanol blend doesn't seem to bother it as much. But as we all know, ethanol doesn't make the power or gas mileage that real gasoline will. I know Indy cars run ethanol but that was a political move to slow down the cars and to please corn farmers.
EDIT: Forgot to add one thing. Avgas octane rating is not the same as car gas octane rating. The avgas rating uses a performance rating. Remember when avgas was called 100/110, or something like that? Car gas octane rating uses the research method plus motor method divided by 2.
R+M equals octane rating.
2
So avgas would come out to somewhere around 80 to 85 on the R+M over 2 method.
But don't listen to me. I don't know squat.